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REMICADE is a chimeric IgG1κ monoclonal antibody with an approximate molecular weight of 149,100 daltons. It is composed of human constant and murine variable regions. Infliximab binds specifically to human tumor necrosis factor alpha (TNFα) with an association constant of 1010 M-1. Infliximab is produce by a recombinant cell line cultured by continuous perfusion and is purifie by a series of steps that includes measures to inactivate and remove viruses. Buy Remicade online
REMICADE is supplie as a sterile, white, lyophilized powder for intravenous infusion. Following reconstitution with 10 mL of Sterile Water for Injection, USP, the resulting pH is approximately 7.2. Each single-use vial contains 100 mg infliximab, 500 mg sucrose, 0.5 mg polysorbate 80, 2.2 mg monobasic sodium phosphate, monohydrate, and 6.1 mg dibasic sodium phosphate, dihydrate. No preservatives are present.
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Remicade is a treatment use to alleviate the symptoms of pain and inflammation in a range of autoimmune inflammatory diseases. Especially psoriatic arthritis and various types of psoriasis, including chronic plaque psoriasis.
Other uses include rheumatoid arthritis, Crohn’s disease, ankylosing spondylitis, and ulcerative colitis.
It is a tumor necrosis factor alpha (TNFα) inhibitor.
How does Remicade work?
Remicade belongs to a class of drugs known as biologics. These are therapies based on proteins that are usually antibodies.
Uses of Remicade
Remicade can be prescribe to treat a number of conditions.
Active psoriatic arthritis: About 15 percent to 30 percent of patients with skin psoriasis also experience joint inflammation.
Moderate to severe rheumatoid arthritis (RA), or rheumatoid diseases: RA is a chronic, progressive autoimmune disease which causes inflammation and pain in the joints and the surrounding tissue, and sometimes other organs. RA can be severely disabling. Used with methotrexate, Remicade can help reduce signs and symptoms of RA.
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